Immunohistochemical Analysis of Vimentin in Oral Submucous Fibrosis
نویسندگان
چکیده
منابع مشابه
Immunohistochemical Analysis of Vimentin in Oral Submucous Fibrosis
Background. Oral submucous fibrosis (OSF), a precancerous condition, is characterized by abnormal accumulation of collagen fibers in oral submucosa. Vimentin is a Class 2 intermediate filament (IF) and primarily expressed in cells of mesenchymal origin. Vimentin is also found to be involved in cell growth, cell cycling, and tumour differentiation. Objective. The purpose of the study was to comp...
متن کاملHistochemical and Immunohistochemical Analysis of Collagen Fibers and Microvascular Density in Various Grades of Oral Submucous Fibrosis
Background and Objective: This study was aimed to evaluate the collagen fibers qualitatively and its correlation with microvascular density in various grades of oral submucous fibrosis (OSMF). Material and Methods: The present study comprised of total 40 cases of oral submucous fibrosis. Picrosirius red staining was done on all the specimens’ sections. ...
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Oral submucous fibrosis is chronic progressive condition of oral cavity. The condition is well recognized for its malignant potential. Usually the disease initiates with redness, blistering, and ulceration inside the mouth. It is characterized by progressive fibrosis of submucosal tissue. The pathogenesis of oral submucous fibrosis is not well understood. Betelquid chewing is the major etiologi...
متن کاملOral Submucous Fibrosis: a case report
We describe an interesting case of oral sub mucous fibrosis accompanied by severe trismus in a 23 years old man. The patient had initially been diagnosed as having internal derangement of the temporomandibular joint and conservative treatment had failed to decrease the symptoms. Despite extremely limited temporomandibular joint movement, cone beam computed tomography revealed no important abnor...
متن کاملimmunohistochemical analysis of syndecan‑1 in leukoplakia and oral submucous fibrosis
background: syndecan‑1 is abundant in normal tissues and reduced in squamous cell carcinomas. leukoplakia and oral submucous fibrosis (osf) are oral pre‑cancerous disorders that have potential for malignant transformation. the aim of this study was to evaluate the expression of syndecan‑1 in leukoplakia and osf and to identify its role as a reliable marker for predicting malignant changes. mate...
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ژورنال
عنوان ژورنال: Journal of Cancer Epidemiology
سال: 2013
ISSN: 1687-8558,1687-8566
DOI: 10.1155/2013/549041